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Resumen
Diverticular disease is highly prevalent in Western countries, affecting up to 60% of individuals over 60 years of age.1 Although most patients remain asymptomatic, a substantial proportion develop complications such as acute diverticulitis and diverticular bleeding.2
Nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin are widely prescribed for analgesic, anti-inflammatory, and cardioprotective purposes. However, cumulative evidence suggests that these medications may increase the risk of diverticular complications.3
Diverticulosis predominantly affects the sigmoid and descending colon and is associated with aging, low-fiber diets, obesity, and physical inactivity.4 Approximately 10-25% of patients with diverticulosis develop diverticulitis during their lifetime.5
Diverticular bleeding is the most common cause for lower gastrointestinal hemorrhage in adults, accounting for up to 40% of cases.6 Risk factors include hypertension, chronic kidney disease, anticoagulant therapy, and NSAID use.7